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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80414e16a2444ff76960ae48ba10c8a8e5307ccc255e1039860277c9a2af4e94' 
  AND token = 'n5NW/ysnMTY1EdjRQlL16ch9nnx2ae4CT4BtT0eKUvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}