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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97181cb0fdb188e5844ebef33dc9fb89f4bc2ea2ed3975129f3fe183b066499e' 
  AND token = 'yHYXh8FRUF9phoASCeF+InvUPjB07vxn8prVNgWy3D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}