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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f68f9e0728d90dc0f055590e563bb3324c730df629fc393789c0176f0661e749' 
  AND token = 'MGhOf7ivF8aLVhqM48DcqqyakYdhKTQM5TnWUFTHSmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}