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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1899f188aa586160bda6dcd5f18091e07c0f8457cd740e5a67b79de203e91d0f' 
  AND token = 'PhGAIj3+PUyBhAWaVRdaWwoRW/GT0/WWH14vDYRC2Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}