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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7574352e4a66e71e6b402884a9b04c0f8cc35237ff15206317cb6f515ece57e0' 
  AND token = 'qcuD8dx+BW7zaUGsar4QrviX8cg5d1SWwlWqOSasZEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}