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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e857ea6fb54cc320fcb46547cddad1303f4d17cf29bb4808bdbc2de12fe07f68' 
  AND token = 'kITo8G+5E/RmozdSakYIJg1BLl61dHYNXIBlD11xnfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}