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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e68b7231b1a2e0857b188e0648985cc75b1b88154fae457f907365687892b4' 
  AND token = 'Fzm2D1xcJlBEtGcoC7DMi23m2sClvJlEpguNOjNvVK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}