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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00a6e94417a59ade2ec3a2765f15e39955c21922b8129804551ca50f29bbcd4' 
  AND token = 'fJKL8je5bLcLRgReqWXv2G0Nxgmb8vFDfD2LfCwtOhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}