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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059305c87d570e3caddf48d7860c08d54766e54faadd0868e623987b3c3b6a71' 
  AND token = 'RFblJaexZ2WDlc23JxYD5o7/vMacuxmMVz8ZwAyPB2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}