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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6449dec051403ee648c103abd8d94898441b969a39529b88a0cd231b53dc7a' 
  AND token = 'MS9dDzdRL3N79wNfmYIgkO7vPcPUYGglaYMKY0Ftx1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}