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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b88a1b1751c68bf0278f11efdeb49d254fded17826ee7ad79ccc42e813f15785' 
  AND token = 'ym1O+/lvXOKvlCaKX/xJN9WGJUTAYP7iQ5nT4OJx6LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}