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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df10eafb77b7403e049cb63acce0ed79cc2293df64f7f466ad1bbc6db1c9e36' 
  AND token = 'aWOA1grrOrTs+ajVOB6bwHu/qFCv10ZgYV90Rj5tjAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}