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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557882d7252805045448e500bb1aaeb4346d06519a9b4055c6aaf1641dedb448' 
  AND token = 'x94SqBPt2W0RfrvLRxEbqYMGkn/Pq1zuwK0N5bKQTQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}