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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c000aaa7b62356106d15257829d55a16241318ee3ebe107cd84226cd0378b11' 
  AND token = 'JVMUJ1xTcnvKZ2VDBquyb4t9/sJ738YphvUdTI0oW9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}