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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5bea75dccc0e4a4b415e7e18aa920d0ff7d9d1589ca4c4ffe92ce90cc2a658' 
  AND token = '3+s+qP1qC95OID98nDTDzCBd0VXJVaq1bURV6aTFDyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}