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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4b50bcb052eba284fad45800ef2f9b135bccc0fb9544705f7b5322247339a9' 
  AND token = 'R8M1XYPr65AyQxHYiU2ugY6afp9XO/6dQ3udyub7TIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}