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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed25b2b48d563dc7dc1242c1645338cd5fbbe83b853efb23c77a011d79b86da0' 
  AND token = 'UTs08Q9++F/wPxwRmMXsqAA66jrX7foSqUUAipBK8FE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}