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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc52f2107a11e22a28ff28859814d515a7b538719e94606168994873122342f5' 
  AND token = 'TTG2vufMJ/tV3krd9Y3fHXWYOeQK7JCncUmWSDWTf9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}