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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318641249f940736c4432ef2372f5bafa9b5ef4b5e13f7318fb540ebeaa3ec91' 
  AND token = '+id0BF3kv/yzM+udqRDViaRZVzuQIfZzxx6R3KCE2Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}