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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd138efd7d5eebce4a9f1fcf999cc4bcf2e4c289153f4e05044e19400c92e0f1b' 
  AND token = '8jO+phH80Lsq2MK25XYWpiqLpJqcnL8b15AcRUTgaXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}