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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a777e48da3c3a070ebb7d8c96c30e1c5e00075e53c1c90e90ca04f1a9ea01aa' 
  AND token = '0rAxJa5n0F0+C7PprejXHyBV+wdcL/TtmTzOw1//4dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}