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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261327061166dc5507845bd05e6a40afe4f37d12e1d0444ea596f4f7d2f07dc9' 
  AND token = '5aq/lAENAZx6rDLxFbkP3G9jwzvFZvcCBiVL6suO9k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}