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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27f44b28475da1f4c302e18e71b7247c6d3678bbd6ab92b3db31b46e84e4eeac' 
  AND token = '+st6sWzjDcNPdPvHZX+Drg6TdYTq25roEa/RBNo3Kfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}