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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38ca6f1a5a9b520ecf535bc49f567ff2ccc26c5e326ba74a53a0424c4f2c304' 
  AND token = 'GGP2t/Dgz/LB10Z38gPBsqsT42OeLu+tbbrsRTrKZIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}