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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefbcc07460974bd30243c0c573b1627bb23efedb93617ee08d56a368494a719' 
  AND token = 'VMosWp+DCT/KHRfofkflfgws74scvz2x1Jb5Qj8cgUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}