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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd37d3d2c0684d554490cd8f3289f6b7a11f808e4f388e45f21766d57a8113c82' 
  AND token = 'QR850voGLWeP5iOmWjICHEdCphPINW10wKGi7NeDcWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}