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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1bff25d72f44ab0bb442208cd78ede9f792e9f6dfd0932dcce55f697be6907' 
  AND token = 'OlxyS5udNLMZ0Tv9SKn7nv1hHvW5vd1OFXEIfBfpM2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}