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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b3a6c317e8df5573c733cb625bcd47def4ecdfdbe712f514b435af8fac3fc8e' 
  AND token = 'f9+IIYtYTuVoL/fGtT5rmGqBY/PTgxbgxvkPTLZ6ZPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}