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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784ee70b34015598cd8a4259d299d3eb0cd5f06d410f25c277b92b1cbde3dbf1' 
  AND token = 'AsO2L61vSiRnEuyebTjUNi8ka8UeN/1QIsEGsw8UEas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}