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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eddcf6c982839fd5c813d075c8af922be36019b3265fb68c0b66fc3f2afc5aa0' 
  AND token = 'sdHwR5oASlFG5x7gkeVJ79yAjt4ZioAvcb6yxyZU8Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}