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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11664825c46889fd4d97364f044ffb8116408dbc7e8be37bae93910bf55c2413' 
  AND token = 'LEuZNR0ueZsFUps+R5j0eBWMW/TAZIpA463k4wS3FxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}