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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab22dc1058348cc958121babbb8aa3f297eb763c3127acef0136e6cac372d159' 
  AND token = 'yp0ygc+V/vmP3kEDY1LQkoKEi12uD5Gvn+dyaflhDD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}