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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc75a4033d5791969a88e8d0ec13d62cd9f87bcb25151d56540ad0e2ff67d99' 
  AND token = 't1KDcR/63Qk3VmFx3T59HKMnTPtZuJGhNwpbhoBdKO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}