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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8224113dc45df1f64f6bd87ac43dcc2437d3e3ac67219113b02497e4cc79068c' 
  AND token = 'sqW2ci4WPQhEf2njwPLdppk650O29dQ4SP+WwTUwPHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}