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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe71ef6e43950318c88227f8162117e2c356018af8d7cdc6575ed02aba65b666' 
  AND token = 'WUt4WYk+lem5n5iXWH8st4S4wQKZsEGzq0nUfzUfUUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}