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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec05be62be043c9331d17a2b43c15b6bde007cee8db8853657c93d195e28dc31' 
  AND token = 'P7zfE8FMtvulqc0hs/lBgSugDFeHjJJH2isRD4RbsEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}