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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8176b4806d07bcb9df57f54776013758b4d11ee45ac03591d880a87d29d70e50' 
  AND token = 'PtYMiRV+jteqPgEKkTf96445Lmk4zzKssH0dFA2lq54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}