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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd410f7e184e470eeacabbb9e0d43752410f7dc355d92ff44d3a673359a1b09' 
  AND token = 'DQkfHsO372E2dsduSqwThKjuxCpkP/PiAMopYy5aSkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}