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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ff0fea7290c40d81e153b20d605b677df7bc7e336df6cc7975e76063b30733' 
  AND token = '8uNPcManMaFKkgH+Fu3bVRWs0PcMQdX0vZiUagCIU4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}