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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d749bc12262ea597209fc994d321815d6eb552c7242b89a6171b262c255cc8d' 
  AND token = 'vf4ixEJW3xdPY8OhcoAkCbOFPZmiHcZDdcKMFJMa1gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}