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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c45c931bce8681014c0b3e88a187a51ccf40c7f7e304f3ded17c9b5dd5bcaa' 
  AND token = '8hU57vq8gsvb6k/XvWPmuw66AI4Va1C5NUdeve7L+Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}