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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e118b035c5c586a0cc701daa68a34e7c6d85c7a22d28d2e00479f984b53b6d' 
  AND token = 'RLTF8OW1/jJsaRWctbZMzvTvdPIHPz1HVN8cRcDBnS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}