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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83581d69579b55d18dacf7a82df1826a83259dbd347c77404301354ce1e3b86a' 
  AND token = 'UQ2t23ZOs1LTHKRusn/giEFHOAkddjsPv4VxLoCNQfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}