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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecff7ed9c1cf1484213ad0bb05bf68647d920aca241c8dc2fd17924a15f54bf' 
  AND token = 'B8ufAq+kH7P06vvde95fw3k73/xSvdg0oCYPos0TQfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}