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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da9b5abfd1d61f3980590e5b9ad0d18b59226cc0e20fd3ec5097d59be63dfaff' 
  AND token = 'Nx546f/M+YFs9tddVkr2hx2kvTv/37TdExL2xoqbtCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}