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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ae568f51537be4dbc8eeab89bfd56d4fcb1f66e79456862d336008a486e35d4' 
  AND token = 'Pd0+L76XMgrFgEnT0NHUr3r+iuBEHw2R8W/LNsiUdhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}