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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8822ec9bf79895a68f94e14ca15a377170232ad56f6d20e3b0f193d01cd4788' 
  AND token = 'PlN93a47L5hsr80Ig6COf0ghbLZvgvwreCdLtokDpQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}