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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf20178b47b775683d5cbdced85825de18bfe66a6527d72d3240d9ddc9d7c3aa' 
  AND token = '3o6NH69nuLwMAvX5gf9rx2sUpm2OivFfd1X5FbhAyHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}