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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a6dfe6ca7d2434cbc20ce4a5965e4c0e073634d681e1de67a739e4c236a792' 
  AND token = 'uhaUCqc7H/BqbPcMYUvK04hb9AqHBl0zlWU8iAK1kz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}