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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265a7b1edea2f3325aac975359f8f1b97f431999a12a2290cf9691a37ae4bb58' 
  AND token = '/kLlFhPzePEFcQ/S8TBQUIe39BBvf2VXSe73q3e+mn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}